Publications
“From bench to bedside”: the clinical significance of BRCA1 gene hypermethylation in breast cancer is a matter of debate. Dr. Maria Luisa Gasparri, Prof. Thorsten Kuehn, Dr. Oreste Gentilini et al. analyzed all available data reporting clinical characteristics of BRCA1 gene hypermethylated breast cancer in women, and found a significant correlation with advanced breast cancer disease, lymph nodes involvement, and pre-menopausal cancer onset in this subset of breast cancer patients.
Despite surgical de-escalation, axillary lymphadenectomy cannot be avoided in some cases. When performed, it may be associated with significant lymphatic morbidity. In this scenario, Dr. Maria Luisa Gasparri, Prof. Thorsten Kuehn, Dr. Oreste Gentilini et al. recently published a meta-analysis evaluating the efficacy of one of the strategies under investigation used to prevent lymphatic morbidity after axillary dissection. Enjoy reading!
The survey was supported by:
- European Breast Cancer Research Association of Surgical Trialists (Eubreast)
- European Society of Mastology (EUSOMA)
- Associazione Nazionale Italiana Senologi Chirurghi (ANISC)
- British Association of Breast Surgeons (ABS)
- Oncoplastic Breast Consortium (OPBC)
- Association for Gynecological Oncology / Arbeitsgemeinschaft Gynaekolocische Onkologie (AGO)
- Scuola Italiana di Senologia
- Collegio dei Senologi Italiani
- Società Svizzera di Senologia/Schweizerische Gesellschaft fuer Senologie/ Societè suisse de Senologie
- Polish Society of Surgical Oncology
- Central Eastern European Breast Cancer Surgical Consortium (CEEBCSC)
- German Cancer Association / Deutsches Krebsgesellschaft
- Hellenic Breast Surgical Society
- Russian Association of Oncological Mammology
- Senaturk

A gap analysis of opportunities and priorities for breast surgical research
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Link "The Lancet Oncology"

Review Articles
Is Axillary Sentinel Lymph Node Biopsy Required in Patients Who Undergo Primary Breast Surgery
Reimer T. · Engel J. · Schmidt M. · Offersen B.V. · Smidt M.L. · Gentilini O.D.
Breast Care 2018;13:324-330 (DOI:10.1159/000491703)
https://www.karger.com/Article/FullText/491703

Editorial
Lymph Node Management in Breast Cancer: A Highly Dynamic Evolution
Kühn T.
Breast Care 2018;13:320-322 (DOI:10.1159/000494043)

What Is the Best Management of cN0pN1(sn) Breast Cancer Patients
de Boniface J. · Schmidt M. · Engel J. · Smidt M.L. · Offersen B.V. · Reimer T.
Breast Care 2018;13:331-336 (DOI:10.1159/000491704)
https://www.karger.com/Article/FullText/491704

Current Status and Future Perspectives of Axillary Management in the Neoadjuvant Setting
Kühn T. · Classe J.-M. · Gentilini O.D. · Tinterri C. · Peintinger F. · de Boniface J.
Breast Care 2018;13:337-341 (DOI:10.1159/000492437)
https://www.karger.com/Article/FullText/492437

Lymph Nodes in Breast Cancer - What Can We Learn from Translational Research
Peintinger F. · Reitsamer R. · Smidt M.L. · Kühn T. · Liedtke C.
Breast Care 2018;13:342-347 (DOI:10.1159/000492435)
https://www.karger.com/Article/FullText/492435

New Technologies for Sentinel Lymph Node Detection
Goyal A.
Breast Care 2018;13:349-353 (DOI:10.1159/000492436)
https://www.karger.com/Article/FullText/492436